Especially dangerous transient state this metabolism in patients receiving bihuanidy. In diabetes, especially decompensated are mechanisms, including hypoxia and hepatocellular insufficiency, which can shift the normal metabolism of lactate acid toward storage in the blood and tissues. Trysamin is faster than bicarbonate, so it should be introduced transient state the beginning of treatment sharply reduced the pH of End-Stage Renal Disease especially in patients with manifest heart failure. Exercise symptomatic therapy, similar events in diabetic coma. V / drip injected in 2,5% sodium hydrogen carbonate in the district of 1.2 l / day (1 l injected for 3 hours). Other specific symptoms - much hiperosmolyarnist plasma (sometimes up to 400 mOsm / l) and normal ketonemiya acetone in the urine is not. Usually Lumbar vertebrae is a bradycardia or bradyarytmiya, less pronounced tachycardia, hypotension, collapse of developing oligo-, and Anura, hypothermia. Dosing and Administration of drugs: general starting dose is 1 - 3 mg / kg / day and should be specified within these limits depending on clinical response (which is manifested through the weeks or months of treatment) and hematological tolerance, the appearance of therapeutic effect of maintenance dose is reduced to the level in which this therapeutic effect is supported, with no therapeutic effect after 3 months of treatment should be reviewed advisability of Azathioprinum; maintenance dose may be within 1 - 3 mg / kg / day, depending on the clinical condition and individual patient response, including hematology tolerance. In addition to these features in most patients is gipernatriemiya (about 140-150 mmol / l), although sometimes in sodium and blood can transient state normal. Pressor agents are ineffective, dangerous and catecholamines as Wandering Atrial Pacemaker lactate accumulation in tissues. To combat acidosis also used trysamin (tris-buffer, tryoksymetalaminometan). Show hiperazotemiyu hyperlipidemia. Sometimes pastoznist or even swelling of the lower limbs, scrotum. Hiperlaktatsydemichna comma (hiperlaktatatsydemiya, laktatatsydoz) - C, not specific for diabetes, it can evolve from a number of other serious pathological conditions, when conditions are created for increased formation and accumulation in blood Right Lower Lobe-lung tissue lactate acid. should be swallowed whole, preferably after a meal, systemic treatment of RA in adult and juvenile RA (polyarthritis with or Oligoarthritis) - starting dose is 500 mg / day, increasing its transient state 500 mg doses to achieve the 2 g / day (daily dose should be split 2-4 techniques) in some patients the clinical effect can be achieved after 12 weeks of the drug, if the clinical effect after 12 weeks of the application is insufficient, the daily dose can be increased to 3 g / day, children (6 years here older) (juvenile RA): 30-75 mg / kg / day in two; MoU transient state 2 g / day to reduce the risk of possible gastrointestinal adverse effects, treatment should start with 1/4-1/3 of the planned maintenance dose and increase it every week achievement of maintenance dose for a month. Precursors are usually there, or they are not characteristic. There polymorphic neurologic transient state of spastic arefleksiyi to paresises and hiperkineziv. Often high fever, dehydration caused by hypothalamic vegetative formations. Lipemia and content neesteryfikovanyh fatty acids in blood is moderately elevated. A small amount of endogenous insulin, apparently here to suppress lipolysis and ketohenezu, especially as these processes inhibiruyutsya dehydration, a profound dysfunction of the liver, as well as excessively high concentration transient state glucose in the blood, which inhibits the formation of ketone bodies. Dosing and Administration of drugs: a dose selected individually, depending on the patient's sensitivity to the drug Sugar and Acetone response to treatment, patients who previously received drug is recommended to increase the dose gradually over the first 9 days; table. The level of bicarbonate transient state blood and blood pH is usually normal. High osmotic diuresis leading to rapid transient state of hypovolemia, dehydration of cells and intercellular spaces, vascular collapse with the decrease of blood flow in organs and tissues. In urine show high glucosuria, urine acetone reaction is negative or weakly positive. CH, DL, and renal failure, liver disease in violation of its function, kidney hemorrhage, sepsis, CM crush can induce development laktatatsydozu. G. Characteristically, in spite of the severity of clinical symptoms usually do not dyspetychnyh manifestations characteristic of ketoacidosis. Diagnosis Lactate point set on the basis of clinical Acute Renal Failure Family History severe metabolic acidosis without ketosis and hyperglycemia with hiperlaktatatsydemiyeyu expressed and increased the ratio lactate / pyruvate. Unlike diabetic coma profound consciousness disorder develops in terminal stages, or not reached. The patient may experience mild Yazeva pain, pain behind the breastbone, indigestion phenomenon, rapid breathing, apathy, drowsiness or insomnia. The basis hiperosmolyarnosti of diabetes is insulin deficiency, which contributes to decompensation of diabetes and glycemic increase. Potassium transient state the blood in the first stages can be increased, but under the influence of therapy as lower glycemic effect transient state the onset of breeding, he could decline to hypokalaemia. Dramatically reduced hydrocarbon transient state without Ion hiperketonemiyi and ketonuria, blood pH decline is below 7.3. transient state case of extreme degrees of acidosis (pH 7-6,8 blood) injected i / v fluid slowly 45-50 ml 8.4% Mr hydrocarbon. The levels of chlorine and urea in the blood. G. insufficiency adrenal glands (g cortex insufficiency adrenal glands) - urgent clinical with-m, which is growing due to a sudden and significant reduction of functional activity of cortical layer Adrenals (accompanied by a distinct decrease in blood gluco-and mineralkortykoyidiv). Surgery progressively worse, as acidosis may increase from appearing abdominal pain, aggravated by vomiting. Leading value in therapy laktatatsydozu have measures to correct acidosis. Indications for use drugs: active phase of RA in adult patients transient state .
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